DO YOU WANT TO KNOW?
Most people do not know they have AMD until they start to lose central vision in one eye. Vision loss can happen quickly and without warning. You do want to know and so does your doctor. With current treatments, AMD may be arrested and, in some cases, improved. the proper eye supplement determined by your personal gene profile and frequent monitoring by your eye doctor are recommended for 'at risk' patients.
A number of factors are shown to increase the risk of developing AMD. Your genetic profile can account for over 60% of this risk, so having a first-degree relative (mother, father, brother, sister) with AMD may significantly increase your risk of developing the disease. In addition to genetics, lifestyle factors like smoking, nutrition, weight and age also play a role in the progression to advanced AMD.
WHAT IS MACULA RISK PGx?
Macula Risk PGx is a combined prognostic and pharmacogenetic DNA test intended for patients who have a diagnosis of early or intermediate AMD. The test is a simple cheek swab taken in your eye doctor's office. Your doctor will order this test to determine:
- Your risk of progression to advanced AMD with vision loss.
- Personalized treatment for maximum preservation of your vision based on your genetic profile.
The prognostic component of the Macula Risk PGx test will calculate your individual risk of progressing to advanced disease with vision loss within 2, 5 and 10 years by analyzing the complete combination of your AMD genes and important non-genetic factors; age, smoking history, BMI and AMD status.
UNDERSTANDING THE MACULA RISK (MR) SCORE
The 10-years risk of progression places the patient in one of 5 Macula Risk categories which can be used by the doctor to assess increased risk, and to customize a disease-management program suited to the patient's individual needs. The Macula Risk (MR) score will range:
From: MR1- Less than 5% risk of progression to advanced AMD within 10 years
To: MR5 - 60-90% risk of progression to advanced AMD within 10 years
PATIENTS WHO ARE AT INCREASED RISK MAY BENEFIT FROM:
- Treatment with personalized preventive eye supplements
- An increased frequency of eye examinations
- Disease education and 'at-home' Amsler Grid testing
- Early diagnosis and treatment of 'Wet' AMD with effective therapies
- Other disease management strategies as determined by the doctor